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Published on: August 25, 2017
Resveratrol: a potential alternative therapeutic agent for patients suffering from chronic obstructive pulmonary
Ong Yan Ren1, Yasmeen Siddiqui2, Mohammed Tahir Ansari3
1Centre of Excellence for Postharvest Biotechnology (CEPB), School of Biosciences, University of Nottingham Malaysia, Semenyih, Selangor Darul Ehsan 43500, Malaysia.
Abstract:
This review explores the therapeutic potential of resveratrol, focusing on its molecular and cellular effects on Chronic Obstructive Pulmonary Disease (COPD), bioavailability enhancement strategies, and development challenges for applications in food, pharmaceuticals, and postharvest sectors. Resveratrol protects lungs by activating SIRT1, reducing oxidative stress via ROS regulation through Nrf2-mediated antioxidant enzymes. It shows promise as an alternative to corticosteroids in COPD and cancer treatment. Encapsulation innovations in resveratrol offer opportunities for food fortification, minimizing risks of chemical degradation and isomerization during storage, paving the way for its broader utility in health and nutrition applications.
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