[Warning: growing number of young-adults with gonorrhea]

Since 2022, an steeply increase has been seen in the number of gonorrhea infections in the Netherlands: in 2023 in the sexual heath centra 31% more cases were found, especially among groups where this is less obvious, such as high educated young women. Gonorrhea infections can be seen with the classic symptoms of an urethritis (the drip). But also asymptomatic or in more severe ways and in different locations. In this clinical lesson we provide 3 examples of gonorrhea infections in young women. In neighboring countries, increasing resistance is being observed for ceftriaxone, the first-choice antibiotic to treat gonorrhea. For adequate treatment and to break the infection chain complete microbiological diagnostics or a test of cure can be necessary. The article ends with prevention measures: condom use and effective partner notification.