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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Blood Transfusion01:15

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
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Viral Recombination00:57

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Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
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Updated: May 23, 2025

Growth, Purification, and Titration of Oncolytic Herpes Simplex Virus
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Oropouche Virus: Implications for Transfusion Services.

Daniele Focosi1, Francesca Colavita2, Silvia Meschi2

  • 1North-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, Italy.

Reviews in Medical Virology
|March 10, 2025
PubMed
Summary
This summary is machine-generated.

A new Oropouche virus (OROV) recombinant strain poses a threat, causing outbreaks in Brazil and Cuba. This review covers OROV knowledge and risk mitigation for blood transfusions.

Keywords:
arbovirusoropouche virustransfusiontransplantation

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Area of Science:

  • Virology
  • Public Health
  • Epidemiology

Background:

  • A novel Oropouche virus (OROV) recombinant strain emerged in 2024.
  • Significant outbreaks have occurred in Brazil and Cuba.
  • Imported OROV cases have been reported in the USA and Europe, highlighting its expanding geographic reach.

Purpose of the Study:

  • To summarize current knowledge on Oropouche virus.
  • To discuss potential risk mitigation strategies.
  • To inform the transfusion community about OROV risks.

Main Methods:

  • Literature review of existing Oropouche virus research.
  • Analysis of outbreak data and case reports.
  • Assessment of transfusion safety protocols.

Main Results:

  • The Oropouche virus is a growing public health concern with recent recombinant emergence.
  • Geographic spread includes South America, the Caribbean, North America, and Europe.
  • Current knowledge gaps and transfusion risks require attention.

Conclusions:

  • The Oropouche virus, particularly new recombinant strains, necessitates enhanced surveillance.
  • Risk mitigation strategies are crucial for ensuring blood product safety.
  • Further research is needed to fully understand and control OROV transmission.