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Related Experiment Videos

Is the MVV:FEV1 ratio useful for assessing spirometry validity?

P Harber, K SooHoo, D P Tashkin

    Chest
    |July 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

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    The maximal voluntary ventilation to forced expiratory volume in one second (MVV:FEV1) ratio is too variable for individual spirometry reliability. However, group averages may assess laboratory performance.

    Area of Science:

    • Pulmonary Function Testing
    • Respiratory Physiology
    • Occupational Health

    Background:

    • The maximal voluntary ventilation (MVV) to forced expiratory volume in one second (FEV1) ratio is a proposed metric for assessing spirometry effort.
    • Its utility in individual disability determinations and clinical applications requires evaluation.

    Purpose of the Study:

    • To investigate the reliability and applicability of the MVV:FEV1 ratio in spirometry.
    • To determine factors influencing the MVV:FEV1 ratio and its potential use in assessing subject effort and laboratory performance.

    Main Methods:

    • Analysis of spirometry data from a large cohort of industrial workers.
    • Validation using a smaller clinical population.
    • Examination of the MVV:FEV1 ratio's correlation with age, lung function impairment, and bronchodilator response.

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    Main Results:

    • The MVV:FEV1 ratio demonstrated significant variability, rendering it unreliable for assessing individual spirometry effort.
    • The ratio was not significantly impacted by age, degree of functional abnormality, or bronchodilator administration.
    • Average MVV:FEV1 ratios across large groups showed potential for evaluating overall spirometry laboratory performance.

    Conclusions:

    • The MVV:FEV1 ratio is not a suitable indicator for determining the reliability of individual spirometry tests.
    • Group-averaged MVV:FEV1 ratios may serve as a valuable tool for quality control and performance assessment of pulmonary function laboratories.