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Updated: May 23, 2025
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Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
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Giant Parathyroid Adenoma Causing Dyspnea: A Rare Clinical Presentation
Tashi Negi1, Vaibhav Saini1, Vikasdeep Gupta1
1AIIMS Bathinda Punjab, Bathinda, 151001 India.
Summary
This case report highlights a rare giant parathyroid adenoma (184g) in South Asia, presenting as cervical swelling and stridor. It underscores the multi-systemic impact of primary hyperparathyroidism and the importance of considering rare presentations.
Area of Science:
- Endocrinology
- Oncology
- Surgical Pathology
Background:
- Primary hyperparathyroidism is a multi-system endocrine disorder.
- Parathyroid adenoma is the most common cause, with giant adenomas (>3.5g) being rare.
- Symptoms arise from hypercalcemia and elevated parathyroid hormone levels.
Purpose of the Study:
- To report the first case of a giant parathyroid adenoma in South Asia presenting with cervical swelling and stridor.
- To discuss the clinical presentation, diagnosis, and management of this rare condition.
Main Methods:
- Case report of a 56-year-old female.
- Clinical presentation: cervical swelling and dyspnea.
- Diagnostic evaluation including biochemical markers and imaging (details not provided in abstract).
Main Results:
- A giant parathyroid adenoma weighing 184g was identified.
- Patient presented with significant cervical swelling and stridor.
- Associated hypercalcemia and elevated parathyroid hormone levels confirmed primary hyperparathyroidism.
Conclusions:
- Giant parathyroid adenoma can present unusually with significant mass effect, causing respiratory distress.
- Early diagnosis and surgical intervention are crucial for managing symptomatic giant parathyroid adenomas.
- This case expands the known spectrum of parathyroid neoplasm presentations in South Asia.
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