Related Experiment Video
Updated: May 23, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
Comparing Different Contrast Injection Methods for Multislice Spiral CT Imaging in Triple-Rule-Out Examinations: A
1Department of Imaging, Lianyungang First People's Hospital, Lianyungang, Jiangsu, People's Republic of China.
Introduction:
The traditional injection method of contrast media (CM) has limitations in terms of volume and imaging quality. Choosing the optimal CM injection method is crucial for ensuring high-quality images and accurate diagnosis in triple-rule-out computed tomography angiography (TRO-CTA). This study aims to investigate the application value of combining region of interest (ROI) with CM injection method alterations in TRO-CTA.
Methods:
A total of 596 patients with chest pain, chest tightness, and dyspnea as the primary clinical symptoms, underwent TRO-CTA examinations based on their clinical symptoms and test indicators. These patients were randomly assigned to one of three groups: the traditional group, the modified group, and the high-pitch helical scan (FLASH) group. Key parameters, including computed tomography (CT) values, vascular filling contrast numbers, image noise, signal-to-noise ratio, contrast noise ratio, image scores, CM volume, CM injection rate, radiation dose of the aorta, pulmonary artery, and coronary artery, were systematically compared across the three groups.
Results:
The CM volume and radiation doses were significantly higher in the traditional group compared to the other groups (P < 0.05). CT values for the aorta and coronary artery in the traditional group were higher than those in the modified and FLASH group, while CT values for the pulmonary artery were lower in the traditional group compared to the modified and FLASH groups (ALL P-value for traditional group versus FLASH group, P-value for modified group versus traditional group < 0.05, P-value for modified group versus FLASH group > 0.05).
Conclusion:
The combination of the modified CM injection method and FLASH scanning mode reduces the required CM volume by nearly 30 mL and significantly decreases radiation dose exposure during the examination. This approach shows valuable potential for improving both the safety and effectiveness of TRO-CTA, with significant implications for clinical practice.
More Related Videos
Related Concept Videos
Radiological Investigation I: X-ray and CT
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

