Related Experiment Video
Updated: May 23, 2025
Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
Impact of Glucose Profile, Fasting Insulin, and Renal Function on Sarcopenia in Elderly at Single Centered Nursing
Alexander Halim Santoso1, Edwin Destra2, Yohanes Firmansyah3
1Department of Nutrition, Faculty of Medicine, Tarumanagara University, Jakarta, Indonesia.
Background:
Sarcopenia, characterized by a progressive decline in muscle mass and strength, poses significant public health challenges for the elderly, impacting physical performance and quality of life. This study aims to investigate the associations between glucose profile, fasting insulin, renal function, and muscle strength among elderly residents of a single-centered nursing home in Indonesia, identifying potential biomarkers for sarcopenia.
Methods:
A cross-sectional analysis was conducted on 31 elderly residents of Santa Anna Nursing Home, with muscle strength measured using handgrip dynamometry and biochemical parameters evaluated through standardized laboratory methods.
Results:
Structural Equation Modeling-Partial Least Squares (SEM-PLS) analysis revealed strong negative correlations between glucose profile (β = -0.683, p < 0.01) and fasting insulin (β = -0.208, p < 0.05) with muscle strength, while renal function showed a moderate positive relationship (β = 0.295, p < 0.05).
Conclusion:
These findings highlight glucose profile, fasting insulin, and renal function as critical predictors of sarcopenia, offering potential pathways for early detection and targeted interventions. Future research should explore longitudinal assessments and molecular mechanisms to refine sarcopenia prevention strategies in aging populations.
More Related Videos
07:22Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
13:35Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
Published on: March 21, 2021
Related Concept Videos
01:15Hypoglycemia and Glucagon
01:19Overview of Carbohydrate Metabolism
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...