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Angioinvasive Mucormycosis and Internal Carotid Artery Thrombosis: A Case Series
Surbhi1,2,3, Atul Anand1, Badal Kumar1
1Otolaryngology - Head and Neck Surgery, Patna Medical College, Patna, Bihar India.
Abstract:
Rhinocerebral mucormycosis is an acute, rapidly progressing, and life-threatening condition that predominantly affects individuals with uncontrolled diabetes and those who are immunocompromised. One critical complication of this disease is the thrombosis of orbital vessels, which can be indicative of angioinvasiveness and predict the subsequent development of cerebral infarctions. In this context, we present a case series of patients with rhino-orbital mucormycosis who experienced complications due to internal carotid artery thrombosis. This case series highlights the severe vascular involvement associated with rhino-orbital mucormycosis and underscores the importance of early recognition and aggressive management to prevent catastrophic outcomes.
Insights
Rhino-orbital mucormycosis can cause severe internal carotid artery thrombosis, leading to dangerous cerebral infarctions. Early diagnosis and aggressive treatment are vital for managing this life-threatening fungal infection.
Area of Science:
- Infectious Diseases
- Vascular Surgery
- Ophthalmology
Background:
- Rhino-orbital mucormycosis is a severe fungal infection affecting immunocompromised individuals, particularly those with diabetes.
- Orbital vessel thrombosis is a critical complication, signaling angioinvasiveness and predicting cerebral infarctions.
Purpose of the Study:
- To present a case series of patients with rhino-orbital mucormycosis complicated by internal carotid artery thrombosis.
- To highlight the significant vascular complications associated with this infection.
Main Methods:
- Case series review of patients diagnosed with rhino-orbital mucormycosis.
- Analysis of vascular complications, specifically internal carotid artery thrombosis.
Main Results:
- Patients presented with rhino-orbital mucormycosis and subsequent internal carotid artery thrombosis.
- This vascular complication was associated with a high risk of cerebral infarction.
Conclusions:
- Rhino-orbital mucormycosis involves severe vascular complications, including internal carotid artery thrombosis.
- Early recognition and aggressive management are crucial to prevent devastating outcomes like cerebral infarctions.
