Arora-Nagarkar Prognostic Classification for Rhinocerebral Mucormycosis©: A Novel Prognostic Classification System
Ripu Daman Arora1, Aakash Aggarwal2, Nitin M Nagarkar3
1Department of Otolaryngology and Head Neck Surgery, All India Institute of Medical Sciences, Raipur, India.
Summary
This study on Covid-19-associated mucormycosis (CAM) found survival rates vary by infection site. A new prognostic classification was developed to predict patient outcomes and guide resource allocation.
Area of Science:
- Infectious Diseases
- Surgical Oncology
- Medical Prognostics
Background:
- Covid-19-associated mucormycosis (CAM) presents significant challenges in patient survival.
- Understanding survival rates based on disease site is crucial for effective management.
Purpose of the Study:
- To correlate overall and disease-specific survival rates with anatomical sites of involvement in CAM patients.
- To develop a novel prognostic classification for mucormycosis to predict long-term patient outcomes.
Main Methods:
- A retroprospective observational study included 175 CAM patients who underwent surgery.
- Data analysis focused on correlating survival rates with sites of mucormycosis involvement.
Main Results:
- Overall survival rate at 24 months was 73.1%.
- Disease-specific survival rates varied significantly by site: Sinonasal (90.16%), Rhinomaxillary (87%), Rhinoorbital (64.7%), and Rhinocerebral (45.45%).
- A statistically significant difference was observed between disease severity and patient outcome.
Conclusions:
- Early diagnosis, timely intervention, and multidisciplinary care contribute to improved survival in CAM.
- The developed "Arora-Nagarkar Prognostic Classification for Rhinocerebral Mucormycosis" (ANPCRM) offers a tool for patient prognostication and resource allocation.
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