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[Ventricular septal defect: late spontaneous closure].

A M Rozza, I Schulze, E W Keck

    Deutsche Medizinische Wochenschrift (1946)
    |June 21, 1985
    PubMed
    Summary

    Most childhood small ventricular septal defects (VSDs) can spontaneously close by early adulthood. Follow-up studies show that nine out of 25 patients achieved complete VSD closure, indicating a positive long-term outcome for many.

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    Area of Science:

    • Pediatric Cardiology
    • Congenital Heart Disease
    • Echocardiography

    Background:

    • Ventricular septal defects (VSDs) are common congenital heart abnormalities.
    • Small VSDs have a variable natural history, with some cases closing spontaneously.
    • Long-term outcomes for isolated small VSDs require further investigation.

    Purpose of the Study:

    • To assess the rate of spontaneous closure in patients with isolated small ventricular septal defects (VSDs).
    • To evaluate the long-term cardiological status of individuals with initially diagnosed small VSDs.

    Main Methods:

    • Retrospective analysis of 25 patients with proven isolated small VSDs in childhood.
    • Follow-up examinations conducted 3 to 19 years later, at ages 20-21 years.
    • Diagnosis of spontaneous closure based on disappearance of murmur and normal cardiological findings.

    Main Results:

    • Spontaneous closure of the VSD was observed in nine out of 25 patients (36%).
    • Six of these patients had a history of follow-up for at least eight years with a confirmed VSD diagnosis.
    • In three patients, closure time could not be precisely determined due to shorter follow-up periods (3-5 years).

    Conclusions:

    • Isolated small ventricular septal defects (VSDs) demonstrate a significant rate of spontaneous closure into early adulthood.
    • Long-term monitoring confirms favorable outcomes for a substantial proportion of pediatric VSD cases.
    • The findings support the potential for non-surgical resolution of certain congenital heart defects.

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