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RETRACTED: Zito Marino et al. AXL and MET Tyrosine Kinase Receptors Co-Expression as a Potential Therapeutic Target in Malignant Pleural Mesothelioma. <i>J. Pers. Med.</i> 2022, <i>12</i>, 1993.

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Related Experiment Video

Updated: May 23, 2025

Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation
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Modified reverse septal flap: A surgical hint.

Gianluca Dalfino1, Andrea Ronchi1, Giorgio Sileo1

  • 1Division of Otorhinolaryngology Head and Neck Surgery, Department of Biotechnology and Life Sciences University of Insubria Varese Italy.

World Journal of Otorhinolaryngology - Head and Neck Surgery
|March 12, 2025
PubMed
Summary
This summary is machine-generated.

A modified reverse septal flap (mRSF) promotes rapid mucosal healing and reduces crusting after endoscopic resection with transnasal craniectomy and skull-base reconstruction, improving patient quality of life.

Keywords:
endoscopic transnasal craniectomyreverse flapseptal flip flapsinonasal malignant tumorskull‐base reconstruction

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Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Oncology

Background:

  • Endoscopic resection with transnasal craniectomy (ERTC) and skull-base reconstruction (SBR) are established treatments for sinonasal and skull-base malignancies.
  • Current SBR techniques often utilize free grafts, but alternative methods like pedicled flaps offer viable reconstruction options.

Purpose of the Study:

  • To describe an inferiorly based septal flap technique designed to enhance mucosal healing and improve patient quality of life following endoscopic endonasal surgery.
  • To present a modified reverse septal flap (mRSF) for nasal floor resurfacing after unilateral ERTC.

Main Methods:

  • Detailed description of the harvesting technique for the mRSF, emphasizing its random vascularization and lower hinge.
  • Application of the mRSF for nasal floor coverage in a patient undergoing unilateral ERTC and SBR for olfactory neuroblastoma.
  • Reconstruction involved fascia lata graft and septal flip flap (SFF) alongside the mRSF.

Main Results:

  • Endoscopic evaluation demonstrated rapid mucosal healing with minimal nasal crusting shortly after surgery.
  • The mRSF facilitated effective resurfacing of the nasal floor defect.
  • The technique proved successful despite adjuvant treatment and early postoperative assessment.

Conclusions:

  • The modified reverse septal flap (mRSF) is a simple and effective method for promoting nasal healing after endoscopic endonasal surgery.
  • This technique offers a viable solution for nasal floor resurfacing, particularly after septal removal in unilateral ERTC procedures.
  • The mRSF contributes to improved patient outcomes and quality of life in skull-base reconstruction.