Pattern of myelination in the pyramidal tract of the rat

The size and myelination of midbulbar pyramidal tract axons were measured by electron microscopy in the rat. We found that myelin thickness did not increase linearly with fiber size; rather, it took on certain preferred thicknesses almost independently of fiber size. This pattern of growth and development is fundamentally different from that of peripheral nerve and may be important for the physiology of the pyramidal tract.