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Post-procedural fever after Transcatheter Aortic Valve Implantation (TAVI). A multi-centric study

Valentina Scheggi1, Yohann Bohbot2,3, Jasim Hasan2

  • 1Cardiothoracovascular Department, Azienda Ospedaliero-Universitaria Careggi and University of Florence, Florence, Italy.

Le Infezioni in Medicina
|March 12, 2025
PubMed
Abstract

Insights

Fever after transcatheter aortic valve implantation (TAVI) is common, often self-limiting, and usually benign. A watchful waiting approach is recommended for stable patients with uncomplicated fever post-TAVI.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Devices

Background:

  • Fever post-transcatheter aortic valve implantation (TAVI) presents diagnostic challenges, with both infectious and non-infectious causes.
  • TAVI can increase infection risk and trigger aseptic inflammatory responses.
  • Standardized management strategies for post-TAVI fever are lacking.

Purpose of the Study:

  • To investigate the incidence, characteristics, and outcomes of fever following TAVI.
  • To evaluate diagnostic and management approaches for post-TAVI fever.
  • To identify factors associated with fever duration and patient outcomes.

Main Methods:

  • Retrospective analysis of 1074 consecutive patients undergoing TAVI.
  • Data collection included demographics, comorbidities, procedural details, and fever occurrence (temperature >37.5°C).
  • Analysis of fever duration, infection markers, antibiotic use, and clinical outcomes.

Main Results:

  • 36.4% of patients developed fever within 2 days post-TAVI; 86% had fever lasting one day.
  • Empiric antibiotics were given to 25% of febrile patients, with infection identified in only 17%.
  • Short-term fever (<1 day) showed similar mortality to no fever; prolonged fever was linked to adverse outcomes.

Conclusions:

  • Fever is a frequent, often benign, complication after TAVI.
  • A watchful waiting strategy is appropriate for stable patients with self-limited fever and no signs of infection.
  • Selected patients may require a more aggressive diagnostic and management approach.
Keywords:
Post-TAVI managementTranscatheter aortic valve implantation (TAVI)antibiotic prophylaxisfeverinfections

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