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Assessing Blood pressure using a doppler ultrasound

Assessing Blood pressure using a doppler ultrasound

To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
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Related Experiment Video

Updated: May 22, 2025

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Published on: July 15, 2015

Enhancing Kidney Quality Assessment: Power Doppler During Normothermic Machine Perfusion.

Yitian Fang¹, Anton V Nikolaev², Jeroen Essers^3,4,5

¹Division of HPB and Transplant Surgery, Department of Surgery, Transplant Institute, Erasmus Medical Center, Rotterdam, the Netherlands.

Artificial Organs

|March 12, 2025

Summary

This summary is machine-generated.

Power Doppler (PD) imaging effectively assesses kidney quality during normothermic machine perfusion (NMP). PD metrics strongly correlate with renal viability, offering a valuable alternative for evaluating marginal donor kidneys.

Keywords:

Doppler ultrasound experimental animal model kidney function quality assessment

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Last Updated: May 22, 2025

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Published on: July 15, 2015

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Published on: March 11, 2016

Ex Situ Normothermic Machine Perfusion of Donor Livers

Ex Situ Normothermic Machine Perfusion of Donor Livers

Published on: May 26, 2015

Area of Science:

Transplantation Medicine
Medical Imaging
Nephrology

Background:

Marginal donor kidneys are crucial for addressing organ shortages in transplantation.
Normothermic machine perfusion (NMP) is an emerging technique for assessing kidney viability.
Objective assessment of kidney quality during NMP is essential.

Purpose of the Study:

To evaluate the added value of Power Doppler (PD) imaging in assessing kidney quality during NMP.
To determine the correlation between PD imaging metrics and kidney function parameters.
To assess the diagnostic accuracy of PD imaging in differentiating kidney viability.

Main Methods:

Porcine kidneys (n=22) underwent 2-hour NMP.
Kidneys were classified into functional groups based on creatinine clearance (CrCl) and oxygen consumption (VO2).
PD imaging metrics (VI, FI, VFI) and renal blood flow (RBF) were measured and correlated with CrCl and VO2.

Main Results:

PD metrics, including vascularization index (VI), flow index (FI), and vascularization flow index (VFI), showed significant correlations with CrCl and VO2.
At 120 minutes, PD metrics demonstrated high diagnostic accuracy (AUC > 0.92) in differentiating kidney function.
Specific cutoff values for VI, FI, and VFI achieved high sensitivity and specificity in identifying lower-functioning kidneys.

Conclusions:

PD imaging metrics strongly correlate with renal viability and function during NMP.
PD imaging provides an effective and potentially superior method for kidney quality assessment compared to traditional RBF measurements.
PD imaging offers a valuable tool for improving the selection of marginal donor kidneys for transplantation.