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Updated: Aug 11, 2026
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Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
Published on: March 20, 2014
Visible-Light-Induced Tandem Nickel-Catalyzed Heck Cyclization/Self-Promoted [2+2] Intermolecular Cycloaddition
Xiaogang Tong1, Linlin Ren1, Yonggong Wang1
1Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Research and Development of Natural Products, School of Pharmacy, Yunnan University, Kunming 650500, China.
Abstract:
Visible-light-induced transition metal (TM) catalysis has emerged as a new paradigm to discover unprecedented transformations. The reported nickel species as TM photocatalysts are mainly involved in the homolysis of Ni(II) complex or alkyl halide activation. Herein, we describe that the photoexcited nickel species could facilitate Heck cyclization by accelerating the anti-β-hydride elimination. Meanwhile, a tandem visible-light-induced substrate self-promoted intermolecular [2+2] photocycloaddition without the assistance of additional photocatalysts was discovered.
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