Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sex Differences in Screening for Large Vessel Occlusion and Thrombectomy: A Population-Based Cohort Study.

Stroke·2026
Same author

Role of Perfusion Parameters on Outcomes and Safety of Endovascular Therapy in Posterior Cerebral Artery Stroke.

Stroke·2026
Same author

Navigating the Complexity and Heterogeneity of Thrombectomy Decision-Making for Medium-Vessel Occlusion Stroke: Where Do We Go From Here?

Stroke (Hoboken, N.J.)·2026
Same author

Sex differences in brain frailty measures and outcomes after endovascular thrombectomy: ESCAPE-NA1 analysis.

Journal of the neurological sciences·2026
Same author

Impact of catheter configuration and proximal blood flow control on intra-arterial cooling for ischemic stroke: an experimental and modeling study.

Journal of neurointerventional surgery·2026
Same author

Safety and Efficacy of Nerinetide at Year 1 in Participants Enrolled in ESCAPE-NEXT: A Multicenter, Double-Blind, Randomized Controlled Trial.

Journal of the American Heart Association·2026

Related Experiment Video

Updated: Jul 4, 2026

Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

20.7K

Do Physicians Intuitively Select Slow Progressors for Thrombectomy in the Extended Time Window?

Salome L Bosshart1,2, Alexander Stebner1,3, Charlotte Zerna4

  • 1Department of Clinical Neurosciences, Foothills Medical Centre, University of Calgary, Calgary, AB, Canada.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|March 12, 2025
PubMed
Summary

For acute ischemic stroke patients treated over 6 hours from last known well, workflow times did not impact clinical outcomes. Favorable baseline imaging suggested selection of slow-progressing cases, mitigating workflow time effects.

Keywords:
imagingpatient selectionslow progressorsstrokethrombectomy

More Related Videos

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
09:52

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

17.1K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

11.8K

Related Experiment Videos

Last Updated: Jul 4, 2026

Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

20.7K
Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
09:52

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

17.1K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

11.8K

Area of Science:

  • Neurology
  • Interventional Radiology
  • Emergency Medicine

Background:

  • Delayed endovascular treatment (EVT) in acute ischemic stroke correlates with poorer outcomes.
  • Investigating workflow times in late-window EVT is crucial for optimizing patient care.

Purpose of the Study:

  • To assess the association between workflow times and clinical outcomes in patients with anterior circulation large vessel occlusion treated > 6 hours from last known well.
  • To determine if pre-hospital and in-hospital times impact modified Rankin Scale (mRS) scores at 90 days.

Main Methods:

  • Retrospective analysis of the prospective, multicenter ESCAPE-LATE cohort study.
  • Included patients with anterior circulation large vessel occlusion treated > 6 hours from last known well.
  • Utilized univariable and multivariable logistic regression to analyze associations between time intervals and outcomes (mRS, NIHSS).

Main Results:

  • No significant association was found between time from last known well to hospital arrival and 90-day mRS.
  • No significant association was observed between time from hospital arrival to arterial access and 90-day mRS.
  • The majority of patients had favorable baseline Alberta Stroke Program Early CT Score (ASPECTS) and collateral status.

Conclusions:

  • Pre-hospital and in-hospital workflow durations did not demonstrate a relationship with clinical outcomes in this late-window EVT cohort.
  • Favorable baseline imaging (ASPECTS, collaterals) may indicate selection of patients with slower stroke progression, potentially explaining the lack of workflow time impact.