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Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
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Updated: May 22, 2025

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Creating a Framework for Minimizing Opioid Consumption after Office Based Surgery.

Austin A Skinner1, Vikranth R Chinthareddy2, Richard D Urman3

  • 1College of Osteopathic Medicine, Kansas City University, Joplin, MO, USA. austin.skinner@kansascity.edu.

Current Pain and Headache Reports
|March 12, 2025
PubMed
Summary
This summary is machine-generated.

The rise in outpatient surgeries necessitates a framework to reduce opioid prescriptions. Careful planning across all surgical phases can enhance patient satisfaction and minimize opioid use.

Keywords:
Office-based SurgeryOpioid sparing Analgesia

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Area of Science:

  • Surgical Innovation
  • Pain Management
  • Public Health

Background:

  • Increasing volume of outpatient surgical procedures in the U.S.
  • Financial incentives driving growth in outpatient and office-based surgeries.
  • Lack of established safety guidelines for perioperative pain management in office-based settings.

Purpose of the Study:

  • Review current trends in opioid prescribing and office-based surgeries.
  • Propose a framework to minimize opioid consumption post-procedure.
  • Address the anticipated rise in opioid prescribing due to increased outpatient procedures.

Main Methods:

  • Systematic review of recent trends in opioid prescribing.
  • Analysis of factors influencing opioid consumption in office-based surgery.
  • Development of a framework for perioperative pain management.

Main Results:

  • Office-based surgery is a rapidly growing sector with increasing outpatient procedures.
  • Inadequate guidelines exist for managing pain in outpatient settings.
  • Increased outpatient procedures may lead to higher opioid prescribing without proper planning.

Conclusions:

  • A structured approach is crucial for managing pain and opioid use after office-based surgery.
  • Consideration of systematic factors at each operative phase is essential.
  • Effective planning can improve patient satisfaction and reduce opioid prescriptions.