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Extraction of Lignin with High β-O-4 Content by Mild Ethanol Extraction and Its Effect on the Depolymerization Yield
Published on: January 7, 2019
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Innovative antimicrobial lignins: Extraction and characterization for advanced hydrogel applications
Nicole Cernekova1, Michal Hricovini2, Pavel Vostrejs1
1Faculty of Chemistry, Brno University of Technology, Purkynova 118, 612 00 Brno, Czech Republic.
International Journal of Biological Macromolecules
|March 12, 2025
Summary
Water-soluble lignin fractions show enhanced antioxidant and antimicrobial properties, making them effective modifiers for hydrogels. These modified hydrogels can be used as active agents against bacteria and oxidative stress.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Antimicrobial Research
Background:
- Lignin's antioxidant and antimicrobial properties are well-known but vary significantly between types.
- Developing water-soluble lignin fractions is crucial for broader applications in material science.
Purpose of the Study:
- To prepare and characterize water-soluble lignin fractions from various sources.
- To evaluate the antioxidant and antimicrobial activities of these fractions.
- To investigate their potential as active modifiers for hydrogels.
Main Methods:
- Preparation of water-soluble lignin fractions (AL, PCFA, PL, GSL).
- Characterization using high-resolution 2D NMR spectroscopy.
- Assessment of antioxidant and antimicrobial activities.
- Modification of carrageenan hydrogels with pyrolytic lignin (PL/F).
Main Results:
- Water-soluble PCFA, PL, and GSL lignins exhibited significantly higher antioxidant activity than original lignins.
- These fractions demonstrated antimicrobial activity against Micrococcus luteus, Serratia marcescens, and Escherichia coli.
- Carrageenan hydrogels modified with 6% PL/F lignin retained viscoelastic properties and showed potent antioxidant and antimicrobial effects.
Conclusions:
- Water-soluble lignin fractions possess enhanced antioxidant and antimicrobial capabilities.
- PL/F lignin can effectively modify carrageenan hydrogels, imparting beneficial properties.
- These modified hydrogels show promise as active biomaterials for various applications.
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