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Updated: May 22, 2025

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Targeting insulin stacking to address overnight hypoglycaemia in hospitalised patients with diabetes
Priyanka Moolchandani1,2, Satya Patel3,2, Tyler Larsen3,2
1Medicine, University of California Los Angeles, Los Angeles, California, USA pmoolchandani@mednet.ucla.edu.
Abstract:
Inpatient hypoglycaemia is a significant concern in patients with diabetes due to its association with increased mortality. At the Veterans Affairs Greater Los Angeles Healthcare System, we developed a project to reduce overnight hypoglycaemia in hospitalised patients with diabetes by addressing insulin stacking, defined as insulin dosed within 4 hours of each other. By delaying the timing of bedtime correctional insulin administration in the electronic health record, we achieved a 28% reduction in the proportion of patients experiencing insulin stacking after one year. This led to significant decreases in overnight hypoglycaemia.
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