Related Experiment Video
Updated: May 2, 2026
05:07
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
521
Association between aortomesenteric angle and symptomatic spontaneous isolated superior mesenteric artery dissection
Yadong Shi1, Yangyi Zhou1, Yuan Yuan1
1Department of Vascular and Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.
Scientific Reports
|March 13, 2025
Summary
A greater aortomesenteric angle (AMA) and hypertension are independent risk factors for spontaneous isolated superior mesenteric artery dissection (SISMAD). Increased AMA significantly correlates with SISMAD occurrence.
Area of Science:
- Vascular Surgery
- Radiology
- Gastroenterology
Background:
- Spontaneous isolated superior mesenteric artery dissection (SISMAD) is a rare condition.
- Understanding risk factors for SISMAD is crucial for early diagnosis and management.
Purpose of the Study:
- To investigate the association between the aortomesenteric angle (AMA) and the occurrence and imaging characteristics of SISMAD.
- To identify risk factors contributing to SISMAD.
Main Methods:
- Retrospective case-control study including 105 SISMAD patients and matched controls.
- Computed tomography angiography (CTA) was used for diagnosis.
- Logistic regression and restricted cubic splines (RCS) analyzed the association between AMA and SISMAD.
Main Results:
- Hypertension, hyperlipemia, and AMA were significantly associated with SISMAD.
- An increasing AMA was an independent risk factor for SISMAD (adjusted OR, 1.03 per 1° increase).
- Larger AMA levels (50-71° and >71°) showed significant associations with SISMAD compared to smaller angles (<50°).
Conclusions:
- Greater AMA and hypertension are independent risk factors for SISMAD.
- AMA is a significant predictor of SISMAD occurrence.
- No clear association was found between AMA and SISMAD imaging characteristics.
Related Concept Videos
01:22Mitral Stenosis I: Introduction
1.8K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.8K
01:15Aortic Regurgitation I: Introduction
1.6K
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.6K
01:22Aortic Regurgitation II: Clinical Features and Diagnostic Tests
1.2K
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
1.2K
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
948
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
948
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
764
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
764
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
589
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
589