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Updated: May 22, 2025

Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
Comparison of different methods for reducing pain during a heel lance in newborns: a randomized trial
Tuğba Karga Yilmaz1, Betul Yavuz2
1Uşak Training and Research Hospital, Uşak, Türkiye.
Background:
This study aimed to compare three different methods [breastfeeding, skin-to-skin contact (SSC), swaddling + holding] to reduce the pain felt by term newborns during a heel lance (HL).
Methods:
This was a randomized three-group experimental study. The study sample included 90 newborns, 30 in each group. The data were collected using a pulse oximeter, a voice recorder, an Information Form, the Neonatal Infant Pain Scale (NIPS). The newborns' pain level, heart rate, and oxygen saturation were measured at three different times.
Results:
No difference was found between the groups' mean NIPS scores before the HL procedure (p > 0.05). The mean NIPS scores 10 s after the procedure started and after the HL procedure were the lowest in the breastfeeding group, followed by the SSC and swaddling + holding groups (p < 0.05). There was no difference between the groups' mean heart rates before the procedure; however, there was a significant difference 10 s after the procedure started and after the procedure (p < 0.05).
Conclusion:
Breastfeeding is the most effective method to reduce pain during and after HL procedures in term newborns, followed by SSC and swaddling + holding.
Trial Registration:
This study was retrospectively registered at ClinicalTrials.gov with the registration number NCT05797532 (date: 04.04.2023).
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