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Bone Health in Paediatric Inflammatory Bowel Disease
Proteek Sen1, Suma Uday1,2
1Department of Endocrinology and Diabetes, Birmingham Women's and Children's NHS Foundation Trust, Birmingham B4 6NH, UK.
Abstract:
Paediatric inflammatory bowel disease (IBD) is often complicated by bone loss resulting in an increased risk of fractures and impaired quality of life. Underlying inflammation, nutritional deficiencies and glucocorticoid therapy are some of the factors contributing to secondary osteoporosis in IBD. Optimising nutrition, dietary supplementation and timely screening are essential in preventing bone loss. Bisphosphonate therapy remains the cornerstone of medical management of osteoporosis. This review explores the various mechanisms contributing towards poor bone health in IBD and the recent advances in diagnostic and preventive approaches along with updates in management strategies.
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