Advances and challenges of mpox detection technology

Area of Science:

• Virology
• Infectious Diseases
• Diagnostic Technologies

Background:

• Mpox, a zoonotic disease caused by the monkeypox virus (MPXV), presents a growing global health challenge.
• Clinical diagnosis relies on laboratory testing, with conventional methods like qPCR and sequencing facing limitations in speed and accessibility.

Purpose of the Study:

• To review current and emerging MPXV detection techniques.
• To identify future research directions for rapid and efficient mpox diagnosis.
• To support the development of strategies for mpox transmission control.

Main Methods:

• Review of conventional MPXV detection methods (qPCR, sequencing, etc.).
• Exploration of emerging technologies, including point-of-care testing (POCT) and biosensors.
• Analysis of advances and challenges in MPXV diagnostic techniques.

Main Results:

• Conventional MPXV detection methods require specialized training and equipment, limiting rapid diagnosis.
• Emerging technologies, such as POCT and biosensors, offer potential for faster and more accessible mpox detection.
• Further research is needed to optimize these novel diagnostic approaches.

Conclusions:

• There is a critical need for advanced MPXV detection methods to address the global health threat of mpox.
• Emerging technologies hold significant promise for improving the speed and efficiency of mpox diagnosis.
• Continued research and development in diagnostic technologies are essential for mpox prevention and control strategies.