Related Experiment Video
Updated: May 22, 2025

A Rapid Method for Multispectral Fluorescence Imaging of Frozen Tissue Sections
Published on: March 30, 2020
[How to optimize intraoperative frozen section examinations in pathology]
Stéphanie Rizzo1, Marie-Sophie Kesteman2, Gilles Leduc2
1Service d'Anatomie et Cytologie pathologique, CHU Liège, Belgique.
Abstract:
The intraoperative frozen section examination allows to offer to the surgeon relevant information which could change the patient intraoperative management. The sensitivity of this technique is limited by the size of the analysed sample and by cryogenisation's artefacts. The intraoperative consultations have to be performed for precise indications because some exams could be harmful. It is mandatory to be aware of different problems which could alter the intraoperative diagnosis: inadequate sampling, technical issues or insufficient communication between the surgeon and the pathologist. Nevertheless, the intraoperative frozen section examination remains a reliable procedure useful in many pathological contexts.

