Decoding the genomic landscape of Mammaliicoccus sp. RAM2 isolated from flacherie-infected Bombyx mori L

Rittick Mondal1, Dipanjan Das1, Sujan Paul1

  • 1Chemical Biology Laboratory, Department of Sericulture, Raiganj University, Raiganj, West Bengal, India.

Insights

This study presents the draft genome sequence of Mammaliicoccus sp. RAM2, an opportunistic pathogen found in silkworms. This genetic information aids in accurate species identification and understanding zoonotic potential.

Area of Science:

  • Microbiology
  • Genomics
  • Zoonotic Diseases

Background:

  • Species within the genus Mammaliicoccus are recognized as opportunistic zoonotic pathogens.
  • Understanding the genetic makeup of these bacteria is crucial for public health and veterinary diagnostics.

Purpose of the Study:

  • To report the draft genome sequence of Mammaliicoccus sp. RAM2.
  • To provide genetic insights for precise species-level identification of Mammaliicoccus.

Main Methods:

  • Isolation of Mammaliicoccus sp. RAM2 from a flacherie-infected Bombyx mori (Nistari race).
  • Whole-genome sequencing and assembly of the isolated strain.

Main Results:

  • The draft genome sequence of Mammaliicoccus sp. RAM2 was successfully generated.
  • The genomic data provides a foundation for differentiating Mammaliicoccus species.

Conclusions:

  • The genome sequence of Mammaliicoccus sp. RAM2 offers valuable genetic markers for accurate identification.
  • This work contributes to the understanding of opportunistic zoonotic pathogens and their hosts.
Keywords:
genomics

Related Concept Videos

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
35.6K
DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
17.1K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
86.7K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
33.1K
Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
4.8K