A case of diplopia masquerading as ptosis: Unveiling a hidden clival chordoma

Neslihan Sevimli1, Güneş Taydaş1, Beril Aycan Yağız1

  • 1Department of Ophthalmology, Fatih Sultan Mehmet Training and Research Hospital, Ataşehir, İstanbul, Turkey.

PubMed

Insights

Chordomas, rare skull base tumors, can cause visual symptoms like ptosis and diplopia. Early diagnosis and evaluation are crucial for managing these ocular manifestations.

Area of Science:

  • Neuro-oncology
  • Ophthalmology
  • Pathology

Background:

  • Chordomas are rare, slow-growing malignant tumors originating from notochordal remnants.
  • Skull base chordomas can present with diverse neurological and visual symptoms due to mass effect.
  • Ocular manifestations, including ptosis and diplopia, are significant indicators of potential skull base pathology.

Purpose of the Study:

  • To report a case of chordoma presenting with visual disturbances.
  • To highlight the association between skull base tumors and ocular symptoms.
  • To emphasize the importance of comprehensive pre-operative evaluation for ptosis.

Main Methods:

  • Case report of a 77-year-old male with new-onset ptosis and diplopia.
  • Diagnostic imaging including computed tomography (CT) to identify a soft tissue mass.
  • Surgical resection of the lesion and histopathological diagnosis of chordoma.

Main Results:

  • Computed tomography revealed a soft tissue mass consistent with a skull base tumor.
  • Histopathology confirmed the diagnosis of chordoma.
  • The patient underwent surgical removal of the tumor, followed by ptosis surgery six months later.

Conclusions:

  • This case illustrates a direct correlation between skull base chordomas and ocular symptoms.
  • Thorough ophthalmological evaluation is essential in patients presenting with ptosis, especially before surgical intervention.
  • Prompt diagnosis and management of chordomas can prevent or alleviate visual complications.