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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Recent advances and perspectives in bioresorbable metal coronary drug-eluting stents
Chengyan Bai1, Xiangyi Feng1, Liang Lan2
1National United Engineering Laboratory for Biomedical Material Modification, Branden Industrial Park, Qihe Economic & Development Zone, Dezhou City, Shandong 251100, People's Republic of China.
Abstract:
Intervention without implantation has become a requirement for developing percutaneous coronary intervention for coronary heart disease. In this paper, the recent advances of three representative types of bioresorbable metal coronary drug-eluting stents (DESs) are reviewed, and the material composition, structural design, mechanical properties and degradability of iron-based, magnesium-based and zinc-based bioresorbable metal coronary DES are analyzed. The methods of regulating the radial strength and degradation rate of the coronary stents are summarized, and thein vivo/in vitroperformance evaluation methods and ideal testing systems of the bioresorbable metal coronary DES are analyzed. Advances made in bioresorbable metal coronary DES, the existing shortcomings and optimization methods are proposed, and the future development direction is prospected.
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