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Updated: May 22, 2025

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
The impact of complication-sensitive risk models on hospital benchmarking for failure to rescue
Arjun Verma1, Saad Mallick2, Justin J Kim3
1Center for Advanced Surgical and Interventional Technology, Department of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA; Harvard Medical School, Boston, MA. Electronic address: https://twitter.com/arjun_ver.
Background:
Failure to rescue has been increasingly used as a surgical quality metric, although implementation with complication-agnostic risk models may disproportionately penalize centers that care for high-risk patients. We used a nationally representative database to assess the impact of complication-sensitive risk models on hospital benchmarking for failure to rescue.
Methods:
All adults undergoing elective coronary artery bypass grafting, aortic/mitral valve replacement, or esophageal/pancreatic/large bowel resection were identified within the 2019 Nationwide Readmissions Database. Two hierarchical logistic regressions (model 1: complication-agnostic; model 2: complication-sensitive) were developed to evaluate risk-adjusted rates of failure to rescue at each center. Patient characteristics (demographics, comorbidities) were incorporated as fixed effects in both models. Model 2 also included adjustment for the occurrence and identity of each complication. Hospitals were subsequently grouped into quintiles of failure to rescue using each model.
Results:
Approximately 296,907 patients at 1,034 hospitals met inclusion criteria. Overall mortality, complication, and failure to rescue rates were 1.1%, 4.8%, and 17.8%, respectively. Centers in the highest quintile of failure to rescue for model 1 more frequently managed patients who developed cardiac arrest (0.9 vs 0.7%, P = .003) or acute kidney injury requiring dialysis (0.6 vs 0.4%, P = .017). In contrast, the rates of all complications except sepsis (2.7 vs 2.3%, P = .035) were comparable between centers in the top quintile and others, when using model 2. Overall, ∼30% of hospitals were reclassified into different quintiles with the complication-sensitive model.
Conclusion:
This study suggests that complication-agnostic models disproportionately penalize centers caring for patients who develop severe complications, which can be mitigated with complication-sensitive models.
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