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Association between short-term exposure to PM2.5 and its components and mumps incidence in Lanzhou, China

Zixuan Zou1, Zhenjuan Li1, Donghua Li2

  • 1Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, Lanzhou, Gansu, China.

Environmental Pollution (Barking, Essex : 1987)
|March 13, 2025
PubMed

Insights

Short-term exposure to fine particulate matter (PM2.5) and its components like organic matter and black carbon are linked to increased mumps incidence. These associations were stronger during warmer months.

Area of Science:

  • Environmental Health
  • Epidemiology
  • Air Pollution Research

Background:

  • Limited research exists on the impact of specific fine particulate matter (PM2.5) components on mumps incidence.
  • Understanding these associations is crucial for public health interventions targeting airborne disease transmission.

Purpose of the Study:

  • To investigate the relationship between individual and combined PM2.5 components and mumps incidence in Lanzhou.
  • To analyze the temporal and spatial patterns of PM2.5 components and mumps cases.
  • To identify key PM2.5 components and their interactive effects contributing to mumps incidence.

Main Methods:

  • Data collection on 6270 mumps cases and PM2.5 components in Lanzhou from 2013-2019.
  • Application of generalized additive mixed models to assess associations.
  • Utilized Bayesian kernel machine regression for evaluating combined and interactive effects of co-exposure.

Main Results:

  • A significant positive correlation was found between PM2.5 concentration and mumps incidence (lag 1 month, RR=1.85).
  • Organic matter (OM) and black carbon (BC) showed significant positive associations with mumps incidence at specific lags.
  • Joint exposure analysis revealed a V-shaped effect, with effects more pronounced in the warm season.

Conclusions:

  • Short-term exposure to PM2.5 and its components (OM, BC) is significantly associated with increased mumps incidence in Lanzhou.
  • The specific components of PM2.5 play a role in mumps risk, with varying effects.
  • Findings highlight the need to consider air quality in public health strategies for mumps prevention.
Keywords:
Air pollutionChemical componentsLagged effectMumpsShort-term exposure

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