Related Experiment Video For Airway invasive aspergillosis (AWIA)
Updated: May 22, 2025
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Imaging findings of multislice computed tomography in 21 patients with airway invasive pulmonary aspergillosis
Xiaoqiong Ni1, Rui Yu1, Jinpeng Hou1
1Department of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Background:
Airway invasive aspergillosis (AWIA) poses a diagnostic challenge due to its nonspecific clinical manifestations. This study aimed to characterize the imaging findings of AWIA and explore the clinical characteristics that facilitate the diagnosis of AWIA.
Methods:
A retrospective analysis was conducted on 21 patients clinically and pathologically diagnosed with AWIA. All subjects underwent chest multislice computed tomography (MSCT) scans, and their clinical data were collected. The computed tomography (CT) features were evaluated, and 17 patients received the follow-up of MSCT in our hospital.
Results:
The high-frequency CT signs with an incidence of ≥60% included lobar and segmental bronchial lumen stenosis and wall thickening, patchy peribronchial consolidation, tree-in-bud sign, nodules (>5 mm), bronchioles wall thickening and lumen expansion. The low-frequency signs with an incidence of <40% included trachea or left/right main bronchial wall thickening, lobar and segmental bronchiectasis and wall thickening, ground-glass opacity, cavity, and pleural effusion. The inter-reader agreement for CT features was substantial (kappa =0.78). Additionally, we observed that clinical symptom improvement did not always correspond with immediate improvement in CT imaging findings during the early stages of treatment.
Conclusions:
The presence of specific high-frequency CT features in patients with underlying risk factors should prompt consideration of AWIA. Early recognition of these CT patterns may facilitate timely diagnosis and treatment, potentially improving patient outcomes.
More Related Videos
15:01Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
Published on: September 18, 2021
10:06Efficient Method for Imaging Murine Lungs that Preserves Spatial Dynamics of Fungal Spores in the Airways
Published on: December 13, 2024
Related Concept Videos
01:30Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
01:10Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
01:20Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...