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Related Concept Videos

The Nativist Approach01:21

The Nativist Approach

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The nativist approach to infant cognitive development proposes that infants are born with inherent knowledge structures that allow them to interpret the world almost immediately. This perspective contrasts with earlier developmental theories, such as those proposed by Jean Piaget, which emphasized a more gradual acquisition of cognitive abilities through interaction with the environment. One key concept in this approach is object permanence — the understanding that objects continue to...
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Related Experiment Video

Updated: May 5, 2026

Functional Mapping with Simultaneous MEG and EEG
06:04

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Published on: June 14, 2010

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Towards personalized precision functional mapping in infancy.

Lucille A Moore1, Robert J M Hermosillo1, Eric Feczko1,2

  • 1Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, United States.

Imaging Neuroscience (Cambridge, Mass.)
|March 14, 2025
PubMed
Summary
This summary is machine-generated.

Researchers mapped individual brain networks in infants using resting-state functional MRI (fMRI). This method reveals unique brain connectivity patterns in newborns, crucial for personalized infant brain mapping and predicting developmental outcomes.

Keywords:
brain developmentinfantsprecision network mappingresting-state fMRIresting-state functional brain networkstemplate matching

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Area of Science:

  • Neuroscience
  • Developmental Neuroscience
  • Brain Imaging

Background:

  • Individual brain functional network topology is highly specific and changes during development.
  • Acquiring high-quality resting-state functional MRI (fMRI) data in infants is challenging but essential for studying individual differences.
  • Understanding early brain development is critical for predicting behavioral and health outcomes.

Purpose of the Study:

  • To develop and validate a method for individualized functional resting-state network mapping in neonates.
  • To assess the individual specificity of brain network topology in early infancy.
  • To determine the data requirements for stable infant functional network maps.

Main Methods:

  • Utilized template matching with generated infant network templates as priors.
  • Applied the method to two independent neonatal resting-state fMRI datasets.
  • Analyzed the topology and individual specificity of detected resting-state networks.

Main Results:

  • Template matching successfully identified major adult resting-state networks in individual infants.
  • Functional network maps demonstrated individual-specific topology in neonates.
  • Network map similarity did not plateau even with 25 minutes of data, indicating higher data needs than in adults.

Conclusions:

  • Individualized functional brain mapping in infants is feasible using template matching with resting-state fMRI.
  • Early functional connectivity patterns are individual-specific, offering potential for personalized medicine.
  • Further research is needed to optimize data acquisition for high-precision infant brain mapping.