Overcoming challenges of recruiting cancer patients into clinical trials: insights from a randomized trial of app-based smoking cessation interventions

  • 0Division of Public Health Sciences, Fred Hutchinson Cancer Center Seattle, WA, USA.

|

|

Summary

This summary is machine-generated.

Social media recruitment for cancer patients in clinical trials is highly effective and cost-efficient. It enrolled significantly more diverse participants for smoking cessation interventions compared to internet or clinic-based methods.

Area Of Science

  • Clinical Trials and Oncology
  • Behavioral Science
  • Health Disparities

Background

  • Recruitment for behavioral clinical trials in cancer patients frequently falls short, particularly for underrepresented populations.
  • Effective recruitment strategies are crucial for enrolling diverse patient groups in cancer research.

Purpose Of The Study

  • To compare the efficacy and cost-effectiveness of social media, internet sites, and clinic-based recruitment strategies.
  • To assess the characteristics of cancer patients enrolled via different recruitment methods in a smoking cessation trial.

Main Methods

  • A randomized trial of app-based smoking cessation interventions compared accrual and cost across three recruitment strategies.
  • Statistical analyses included Fisher's exact tests and analysis of variance to compare participant data.
  • Participant characteristics (sociodemographic, cancer type/stage, smoking habits) were analyzed by recruitment source.

Main Results

  • Social media recruited 79.6% of participants, significantly outperforming internet (10.1%) and clinic (9.8%) methods.
  • Social media recruitment was the most cost-effective, with a cost per participant of $270 compared to $454 (internet) and $2,240 (clinic).
  • Social media attracted a more socioeconomically diverse group, including those with low income and later-stage cancers, while clinics recruited older adults and Hispanic participants.

Conclusions

  • Social media is a highly efficient and cost-effective strategy for recruiting a diverse sample of cancer patients into behavioral clinical trials.
  • Utilizing social media platforms can significantly improve the enrollment of underrepresented populations in cancer research.
  • This approach holds substantial potential for enhancing recruitment in future behavioral oncology trials.

Related Concept Videos

Longitudinal Research 02:20

11.8K

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...

Statistical Methods for Analyzing Epidemiological Data 01:25

275

Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:

Descriptive Statistics: These provide basic...

Cancer Survival Analysis 01:21

315

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...

Cancer Prevention 02:59

6.0K

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

Combination Therapies and Personalized Medicine 02:50

4.8K

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...