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Advances in total antioxidant capacity detection based on nanozyme
Jiaoyuan Fang1, Yun Wang1, Yihan Jiang1
1College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang, 471023, China.
Talanta
|March 15, 2025
Summary
Nanozymes mimic enzymes for biosensing applications. This review explores nanozyme-based sensors for determining total antioxidant capacity (TAC), highlighting their potential and challenges.
Area of Science:
- Biomaterials Science
- Analytical Chemistry
- Nanotechnology
Background:
- Nanozymes are nanomaterials with enzyme-like catalytic properties.
- Total antioxidant capacity (TAC) is vital for food quality and health assessment.
- Nanozymes with peroxidase (POD)-like and oxidase (OXD)-like activity are used for TAC determination.
Purpose of the Study:
- To review nanozyme catalytic activities for TAC determination.
- To discuss the design principles of nanozyme-based TAC sensors.
- To classify applications of nanozyme sensors in TAC determination.
Main Methods:
- Literature review of nanozyme-based sensors for TAC.
- Analysis of enzyme-mimicking catalytic activities.
- Classification of sensor applications and evaluation of future prospects.
Main Results:
- Nanozymes offer versatile platforms for TAC sensing.
- Various nanozyme architectures are employed for enhanced sensor performance.
- Significant progress has been made in applying nanozyme sensors for TAC determination.
Conclusions:
- Nanozyme-based sensors show great promise for accurate TAC assessment.
- Further research is needed to address challenges and optimize sensor development.
- This review provides insights into the opportunities and challenges in the field.

