Related Experiment Video
Updated: May 22, 2025

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
Published on: May 18, 2022
An artificial intelligence-informed proof of concept model for an ecological framework of healthy longevity forcing
Ross Arena1, Shuaijie Wang2, Nicolaas P Pronk3
1Department of Physical Therapy, College of Applied Science, University of Illinois, Chicago, IL; Healthy Living for Pandemic Event Protection (HL - PIVOT) Network, Chicago, IL, USA; HealthPartners Institute, Minneapolis, MN, USA.
Abstract:
Unhealthy lifestyle behaviors are a doorway to downstream health consequences characterized by the following: 1) poor quality of life and diminished mobility; 2) increased likelihood of chronic disease risk factors and diagnoses; and, ultimately, 3) a shorter lifespan and healthspan. The aim of the current study is to assess if an ecological framework can predict U.S. lifespan via the use of artificial intelligence. The current study utilized several U.S. county-level datasets representing the predictive variables of the ecologic framework. A non-linear artificial intelligence statistical approach was used to assess the ability of these variables to predict life expectancy, death rate, and years of life lost. The R² values demonstrated that the performance of Extra trees models was different across the three outcomes, however, death rate always exhibited the highest R² for each feature number, indicating superior model accuracy for this outcome. Generally, an increase in the number of features led to improved model performance. Variables from all factors included in the proposed ecological framework were retained in the final predictive models. There is a need to understand why individuals/families/community, connected by shared cultural beliefs, decide to make one lifestyle behavior decision over another.
Related Concept Videos
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Stress Prevention and Stress Management Techniques VI
Motivation and Self-Determination
Motivation, the driving force behind behavior, plays a pivotal role at every stage of the change process. The research...
Longitudinal Research
Erikson's Theory on Socioemotional Development during Adulthood
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
Mechanistic Models: Compartment Models in Individual and Population Analysis
Cognitive Development During Adulthood

