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Insensible water loss in extremely preterm infants cared for in incubators with 70% and 90% relative humidity
Narendra Dereddy1,2, Deborah Ruth3, Jianbin Zhu4
1Center for Neonatal Care, Advent Health for Children, Orlando, FL, 32804, USA. narendra.dereddy.md@adventhealth.com.
Objective:
To determine the insensible water losses (IWL) in preterm infants cared for in incubators with 70% or 90% relative humidity (RH).
Study Design:
This was a single center retrospective study of extremely preterm infants between 22- and 28-weeks gestational ages nursed in 70% and 90% RH. IWL was calculated using a formula that utilized infants' fluid intake, urine output and body weight changes. IWL between the two groups were compared using independent t-test. Multivariate linear regression was used to assess the effects of humidity on IWL after adjusting for confounding variables.
Results:
IWL was higher in infants nursed in 70% RH when compared with those nursed in 90% RH (47.7 ± 30.3 vs. 28.8 ± 39.6, p = 002). Multivariate linear regression analysis showed that RH has an independent effect on the insensible water loss.
Conclusion:
Extremely preterm infants nursed in incubator with 70% RH have higher IWL than infants nursed in 90% RH.
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