Related Experiment Video
Updated: May 22, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Association between osteoporosis and periodontitis
Françoise Tilotta1, Marjolaine Gosset2, Julia Herrou3
1Université Paris Cité, INSERM UMR 1153, AP-HP Centre, Hôpital Cochin, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France; Université Paris Cité, INSERM UMR 1333 Oral Health, 1, rue Maurice-Arnoux, 92120 Montrouge, France; Service de Médecine Bucco-Dentaire, AP-HP, Hôpital Louis-Mourier, 92700 Colombes, France.
Osteoporosis and periodontitis both involve bone loss and share common risk factors. Early detection and management are crucial for preventing fractures and tooth loss.
Area of Science:
- Oral Health and Bone Metabolism
- Systemic Health Implications
Background:
- Osteoporosis and periodontitis are common, costly diseases characterized by bone resorption.
- Both conditions significantly impact public health globally.
- Understanding their relationship is key for prevention.
Purpose of the Study:
- To highlight the link between osteoporosis and periodontitis.
- To emphasize the importance of interdisciplinary patient management.
Main Methods:
- This study is a review of existing literature on osteoporosis and periodontitis.
- It synthesizes information on shared pathophysiology and clinical implications.
Main Results:
- Both diseases involve the destruction of bone tissue.
- A strong association exists between severe periodontitis and reduced bone density.
- Patients with one condition are at higher risk for the other.
Conclusions:
- Dental professionals should refer patients with severe periodontitis for bone density assessment.
- Rheumatologists should advise osteoporosis patients to maintain regular dental check-ups.
- Integrated care can prevent fractures and tooth loss.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Osteoclasts in Bone Remodeling
Bone Remodeling
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...

