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Current Applications and Developments of Natural Language Processing in Kidney Transplantation: A Scoping Review
René Gatsinga1, Rachel Shu-En Lau1, Benjamin Jia Han Lim1
1Department of Urology, Singapore General Hospital, Singapore, Singapore.
Transplantation Proceedings
|March 16, 2025
Summary
Natural language processing (NLP) tools are revolutionizing kidney transplantation by improving early diagnosis, predicting outcomes, and optimizing organ utilization. These AI advancements enhance patient care and policy-making in transplant medicine.
Area of Science:
- Artificial Intelligence
- Medical Informatics
- Nephrology
Background:
- Natural Language Processing (NLP) is an AI subfield enabling computers to process human language.
- NLP tools are increasingly vital in modern life and medical research.
- Their application in kidney transplantation medicine is rapidly expanding.
Purpose of the Study:
- To conduct a scoping review of current and future applications of NLP in kidney transplantation.
- To evaluate the impact of NLP on diagnosis, outcome prediction, and organ utilization.
- To assess NLP's role in public perception and policy-making for transplant care.
Main Methods:
- Electronic literature search on PubMed, EMBASE, and Scopus.
- Inclusion of ten studies after independent review and conflict resolution.
- Analysis of NLP applications in clinical and research settings within kidney transplantation.
Main Results:
- NLP aids in early renal disease diagnosis and predicts graft loss/complications.
- NLP can predict organ viability, potentially improving organ utilization.
- Analysis of social media and news comments using NLP gauges public perception and informs policy.
Conclusions:
- NLP tools are significantly impacting kidney transplantation medicine.
- Potential exists to improve early diagnosis, predict outcomes, and enhance organ utilization.
- NLP is poised to revolutionize renal transplantation with wider EHR adoption and technological advancements.

