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Predictive model for optimizing prehospital transfusions in an urban EMS system.
Bo Zeng1, Joshua Brown2,3, Zhengsong Lu1
1Department of Industrial Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Transfusion
|March 17, 2025
Summary
Optimizing prehospital transfusions with mobile blood banks (MBBs) can significantly reduce patient transfusion times. Computer modeling suggests deploying two MBBs can service 73% of eligible injured patients, improving survival rates.
Area of Science:
- Emergency medicine
- Health services research
- Operations research
Background:
- Prehospital transfusions can improve survival for trauma patients.
- Blood products are scarce, necessitating efficient deployment strategies.
- Mobile blood banks (MBBs) offer a potential solution for timely transfusions.
Purpose of the Study:
- To optimize the deployment of two mobile blood banks (MBBs) in Pittsburgh using computer modeling.
- To evaluate the impact of MBB deployment on transfusion times for injured patients with hypotension.
- To determine the optimal number of MBBs for servicing eligible patients.
Main Methods:
- Mixed integer programming was used to identify optimal MBB base locations.
- Discrete-event simulation modeled MBB dispatching using one year of 911 call data.
- The study focused on injured patients experiencing hypotension.
Main Results:
- MBB-administered transfusions averaged 7.2 minutes, significantly faster than hospital transfusions (36.7 minutes).
- Two MBBs could service up to 73% of eligible patients; four MBBs serviced up to 95%.
- Deploying more than four MBBs yielded diminishing returns in patient servicing.
Conclusions:
- Computer modeling is valuable for resource optimization in prehospital transfusion programs.
- Strategic MBB deployment can enhance emergency medical services and patient outcomes.
- Efficient resource allocation is crucial for maximizing the benefit of scarce blood products.

