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Updated: May 22, 2025

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Cutting-Edge Advancements in the Antibiotics-Gut Microbiota-Urinary Tumour Axis

Jie Wang1, Dengxiong Li1, Ruicheng Wu1,2

  • 1Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Cell Proliferation
|March 17, 2025
PubMed

Insights

The gut microbiome influences urological tumors and their treatment. While antibiotics can disrupt this balance, certain bacteria may boost anti-tumor immunity and overcome treatment resistance.

Area of Science:

  • Urology
  • Oncology
  • Microbiology

Background:

  • The gut microbiota plays a crucial role in regulating the development and progression of urological tumors.
  • Dysbiosis, often induced by antibiotics, can significantly alter the tumor microenvironment and impact therapeutic efficacy.
  • Specific bacterial species have demonstrated potential in modulating anti-tumor immunity and addressing endocrine resistance in urological cancers.

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