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Effect of potassium nitrate on tooth sensitivity during in-office bleaching: A randomized clinical trial
Deise Caren Somacal1, Melissa Castro do Rio1, Hélio Radke Bittencourt2
1Department of Restorative Dentistry, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Background:
The study is a triple-blind, split-mouth, randomized trial to evaluate and to compare the effect of different concentrations of potassium nitrate (PN) prior to in-office bleaching on tooth sensitivity (TS).
Material And Methods:
Sixty participants were randomly divided into groups (n=30): Group A: 5% PN (positive control) and 10% PN; and Group B: 5% PN (positive control) and 35% PN. Each concentration of PN was applied to a hemi-arch for 10 min, and then a 35% bleaching agent was applied. The participants underwent two sessions of bleaching with a one-week interval. TS was recorded using a questionnaire and a visual analog scale.
Results:
According to McNemar's test, there was a significant reduction in the prevalence of TS in group A (p=0.013) and group B (p=0.000) across the time assessments. Fisher's Exact Test showed no significant difference between the control and treatment sides (p>0.05). There was a significant reduction in TS intensity for both groups (p<0.05).
Conclusions:
The 10% and 35% PN were effective in reducing the prevalence and intensity of TS, as well as 5% PN, and the treatments did not affect color change. Key words:Clinical trial, dentin sensitivity, tooth bleaching, hydrogen peroxide, potassium nitrate.

