Superior vena cava syndrome due to hyper-homo-cysteinemia: A rare case report

Superior vena cava (SVC) syndrome (SYN) is a relatively frequent complication observed in patients with malignancies and is frequently characterized as a medical emergency. In most instances, it arises from mechanical obstruction of the SVC caused by extraluminal compression from primary intrathoracic malignancies. Intraluminal obstruction (OB) resulting from thrombosis (TMBO) may also lead to the manifestation of symptoms and signs associated with the syndrome. Clot-related SVC OB is primarily linked to the presence of indwelling central venous catheters and pacemaker leads. However, data shows that this is due to hyper-homo-cysteinemia (HY-HM-CT).