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Updated: May 22, 2025

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
PSMA-Uptake Reveals Globet Cell Cancer of the Appendix in a Patient Staged for Prostate Cancer With PET/CT
Nina A Lampe1, Nina Anzic2, Joe Stürmlin3
1Department of Radiology and Nuclear Medicine, Cantonal Hospital Lucerne, Lucerne.
Abstract:
18 F-PSMA 1007 is an established tracer for staging intermediate and high-risk prostate cancer. Besides prostate cancer cells, benign tumors and inflammations/infections can show unspecific PSMA uptake. We present a case of incidental PSMA uptake of the appendix revealing a globet cell adenocarcinoma in histology after surgical resection. Globet cell tumors are rare neoplasms of the appendix. Patients with incidental PSMA uptake in the appendix should undergo further work-up.

