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Recent Advances in Colorimetric and Fluorescent Chemosensors for Cu2⁺ Ions: Trends, Challenges, and Future Directions
1Department of Chemistry, Rajalakshmi Engineering College, Chennai, 602105, India. udhaya.nit89@gmail.com.
Abstract:
The detection of copper ions (Cu2⁺) through colorimetric and fluorometric methods has garnered significant attention due to the biological, environmental, and medical importance of Cu2⁺. These detection techniques have proven to be highly effective due to their simplicity, cost-efficiency, high sensitivity, and suitability for bioimaging applications. This critical review begins by briefly addressing the sources, applications, and toxicity of copper ion sensors. It then provides an in-depth classification of fluorescent and colorimetric Cu2⁺ sensors based on their receptors, organizing them into various categories such as anthracene, pyridine, pyrazole, pyrrole, naphthalene, imidazole, and quinoline functionalized sensing systems, with a focus on developments since 2016.
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