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Machine Learning-Based Model for Grip Strength Prediction in Healthy Adults: A Nationwide Dataset-Based Study
Mina Park1, Yeo Hyung Kim1, Jung Soo Lee1
1Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Journal of Clinical Medicine
|March 17, 2025
Summary
Machine learning models accurately estimate handgrip strength (HGS) in adults. The XGBoost model demonstrated superior predictive accuracy and generalizability for clinical applications.
Area of Science:
- Health Sciences
- Biomedical Engineering
- Data Science
Background:
- Handgrip strength (HGS) is a key indicator of overall health and functional status.
- Accurate estimation of HGS is crucial for early diagnosis and personalized interventions.
- Existing methods for HGS assessment may have limitations in large-scale population studies.
Purpose of the Study:
- To develop and compare machine learning models for estimating HGS in healthy adults.
- To identify the most accurate and generalizable model for HGS prediction.
- To explore key predictors influencing HGS estimation.
Main Methods:
- Analysis of data from 21,147 Korean adults (aged >19 years) from 2014-2019.
- Development and evaluation of Polynomial Regression (PR), Multilayer Perceptron (MLP), and Extreme Gradient Boosting (XGBoost) models.
- Utilized demographic, anthropometric, and physical activity data as predictors; assessed models using RMSE and R².
Main Results:
- HGS varied significantly by gender, age, and hand dominance, with males and younger individuals exhibiting higher strength.
- The XGBoost model achieved the highest predictive accuracy and generalizability, with an R² of 0.717.
- Key predictors for HGS in the XGBoost model included weight, age, height, and waist circumference.
Conclusions:
- The XGBoost model demonstrated superior performance over PR and MLP for HGS estimation.
- Accurate HGS estimation using machine learning holds significant potential for clinical applications.
- This approach can support early disease detection, targeted interventions, and personalized health goal setting.

