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Arrhythmia-Induced Cardiomyopathy: Predictors of Improvement in Left Ventricular Systolic Function After Catheter

Marisa Varrenti1, Eleonora Bonvicini2, Matteo Baroni1

  • 1Electrophysiology Unit, De Gasperis Cardio Center, Niguarda Hospital, 20162 Milan, Italy.

Journal of Clinical Medicine
|March 17, 2025
PubMed

Insights

Identifying predictors of left ventricular recovery after catheter ablation for arrhythmia-induced cardiomyopathy (AIC) is crucial. This review synthesizes evidence to find reliable indicators for successful reverse remodeling in AIC patients.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiomyopathy Research

Background:

  • Arrhythmia-induced cardiomyopathy (AIC) involves left ventricular systolic dysfunction reversible upon arrhythmia resolution.
  • Catheter ablation is a primary treatment, but predicting ventricular recovery post-ablation remains challenging.

Purpose of the Study:

  • To identify robust predictors of left ventricular systolic recovery in patients with AIC following catheter ablation.
  • To synthesize current evidence on factors influencing reverse remodeling after ablation for AIC.

Main Methods:

  • Systematic review of observational studies focusing on AIC patients undergoing catheter ablation.
  • Analysis of diagnostic modalities including echocardiography, cardiac MRI, ECG, and biomarkers.

Main Results:

  • Echocardiography and cardiac MRI are key for diagnosis.
  • Electrocardiograms and laboratory biomarkers offer additional predictive insights.
  • A definitive framework for selecting optimal ablation candidates is still needed.

Conclusions:

  • Robust predictors for systolic recovery in AIC patients post-ablation are being identified.
  • Further research is needed to establish a comprehensive model for predicting reverse remodeling.

Keywords:
arrhythmia-induced cardiomyopathycardiac magnetic resonancecatheter ablationheart failureleft ventricular systolic function

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