Related Experiment Video
Updated: May 21, 2025

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
Published on: April 4, 2025
Pediatric Chronic Kidney Disease During Pandemic Conditions-A Single-Center Experience
Łukasz Biesiadecki1, Joanna Jacuńska1, Paulina Tomecka1
1Students' Scientific Association, Department of Pediatric Nephrology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.
Insights
The COVID-19 pandemic delayed pediatric chronic kidney disease (CKD) diagnosis, with more children diagnosed at advanced stages. Reduced healthcare access likely contributed to these delays in diagnosing CKD in children.
Area of Science:
- Pediatric Nephrology
- Public Health
- Epidemiology
Background:
- Chronic kidney disease (CKD) prevalence is rising globally, including in children.
- Early diagnosis of pediatric CKD is crucial but challenging.
- External factors, like the COVID-19 pandemic, may disrupt diagnostic pathways.
Purpose of the Study:
- To investigate the impact of the COVID-19 pandemic on the diagnosis of pediatric chronic kidney disease (CKD).
- To compare CKD diagnosis in children before and during/after the pandemic.
- To analyze CKD stage, underlying causes, and sex differences at diagnosis.
Main Methods:
- Retrospective analysis of 154 pediatric CKD patients.
- Comparison of prepandemic (2015-2019) and pandemic/postpandemic (2020-2024) cohorts.
- Evaluation of estimated glomerular filtration rate (eGFR), CKD stage, etiology, and sex.
Main Results:
- Comparable numbers of pediatric CKD diagnoses between periods.
- Higher proportion of advanced CKD stages in the pandemic/postpandemic cohort.
- Increased incidence of glomerulopathies, acute kidney injury, and unknown CKD causes during the pandemic.
Conclusions:
- The COVID-19 pandemic likely delayed pediatric CKD diagnosis.
- Reduced primary care access and disrupted check-ups may be contributing factors.
- This highlights potential long-term impacts on pediatric kidney health surveillance.
Abstract:
Background/Objectives: The prevalence of chronic kidney disease (CKD) is increasing worldwide, and this tendency is also visible in pediatric patients. The major clinical challenge is to achieve a diagnosis as early as possible, despite an overt clinical course, especially in the early stages of the disease. Unfavorable external conditions may disturb the proper treatment of chronically ill patients and delay the time of diagnosis. The recent COVID-19 pandemia might have altered the usual diagnostic pathways of different comorbidities, and CKD was probably one of them. However, there are no data on newly diagnosed CKD in children during the time of the pandemia, so our aim was to approach this problem. Methods: We analyzed medical records of 154 children with CKD who were hospitalized in the Department of Pediatric Nephrology in prepandemic (years 2015-2019) vs. pandemic and postpandemic (2020-2024) conditions, analyzing the eGFR value and stage of CKD at diagnosis, the underlying diseases leading to CKD, and sex-related differences. Results: The number of patients who were diagnosed with CKD in both time periods was comparable. Children hospitalized in the years 2020-2024 presented more often with advanced stages of CKD. The trend towards an increasing share of glomerulopathies, acute kidney injury, and unknown causes of CKD was noticeable under pandemic conditions. Conclusions: The COVID-19 pandemic could, probably owing to reduced access to primary healthcare and disrupted routine check-ups, delay the process of diagnosing CKD in children.
Related Concept Videos
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Nephrons

