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Limb Salvage in Patients with Concomitant Advanced Malignancy.
Jolyn Hui Qing Pang1, Nick Zhi Peng Ng2
1Department of General Surgery, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.
Journal of Clinical Medicine
|March 17, 2025
Summary
Patients with advanced cancer and chronic limb threatening ischemia require a holistic treatment approach. This article proposes a new management algorithm to improve patient quality of life.
Area of Science:
- Vascular Surgery
- Oncology
- Patient Management
Background:
- Increasing prevalence of advanced malignancy co-occurring with chronic limb-threatening ischemia.
- Challenges in managing complex cases involving both advanced cancer and severe limb ischemia.
Observation:
- Current treatment paradigms may not adequately address the multifaceted needs of these patients.
- Advancements in medical and surgical techniques offer new possibilities for intervention.
Findings:
- The article presents a novel, holistic approach to managing patients with advanced malignancy and chronic limb-threatening ischemia.
- A proposed clinical algorithm guides treatment decisions for this complex patient population.
Implications:
- This approach aims to enhance the quality of life for patients facing advanced cancer and limb ischemia.
- The proposed algorithm can assist vascular surgeons in optimizing care and improving patient outcomes.

