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Related Experiment Videos

Rania Hammami1, Aymen Dammak2, Faiza Safi3

  • 1Sfax University, University of Medicine, Cardiology Department, Military University Hospital of Sfax, Tunisia.

La Tunisie Medicale
|March 17, 2025
PubMed
Summary

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This summary is machine-generated.

The incidence of arterial and venous thromboembolic events in ambulatory COVID-19 patients is low (0.9%). Hormonal contraception and moderate COVID-19 increase risk, while physical activity is protective. Rivaroxaban and LMWH showed similar safety and efficacy.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pharmacology

Background:

  • Limited data exists on thromboembolic (TE) event incidence and predictors in ambulatory COVID-19 patients.
  • Understanding these risks is crucial for effective patient management.

Purpose of the Study:

  • To analyze TE complications in outpatient COVID-19 cases.
  • To compare the efficacy and safety of Rivaroxaban versus low molecular weight heparins (LMWHs) for thromboprophylaxis.

Main Methods:

  • Observational study of 2089 COVID-19 outpatients (Oct 2020 - Dec 2021).
  • Analysis of TE event predictors and thromboprophylaxis treatments.
  • Comparison of Rivaroxaban and LMWH outcomes.

Main Results:

Keywords:
COVID-19Low Molecular Weight HeparinRivaroxabanhemorrhagic eventsthromboembolic events

Related Experiment Videos

  • The incidence of arterial and venous TE complications was 0.9%.
  • Predictors included hormonal contraception, moderate COVID-19, recent surgery/miscarriage, and CT lung signs; physical activity was protective.
  • Rivaroxaban and LMWH demonstrated comparable rates of TE events and major bleeding.

Conclusions:

  • Thromboembolic complications are infrequent in ambulatory COVID-19 patients.
  • Specific risk factors and protective elements were identified.
  • Rivaroxaban and LMWH are similarly effective and safe for thromboprophylaxis in this population.