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Transfer learning-enhanced CNN-GRU-attention model for knee joint torque prediction
Hao Xie1, Yingpeng Wang2, Tingting Liu1
1School of Biomedical Engineering, Capital Medical University, Beijing, China.
Frontiers in Bioengineering and Biotechnology
|March 18, 2025
Summary
This study introduces a novel CNN-GRU-Attention neural network model to accurately predict knee joint torque. The model, enhanced with transfer learning, improves prediction accuracy both within and between subjects for injury prevention.
Area of Science:
- Biomechanics
- Sports Science
- Machine Learning
Background:
- Accurate joint torque prediction is crucial for injury prevention, offering insights into forces during activities.
- Traditional methods using surface EMG (sEMG) and kinematics struggle with complex movements and individual variability.
- Generalizing joint torque estimation models across subjects is challenging due to declining feature transferability.
Purpose of the Study:
- To develop a more accurate knee joint torque prediction model.
- To address the limitations of traditional methods in capturing non-linear muscle activation-joint motion relationships.
- To enhance model generalizability across different individuals using transfer learning.
Main Methods:
- Proposed a hybrid CNN-GRU-Attention neural network model informed by a neuromusculoskeletal (NMS) solver.
- Integrated transfer learning to improve inter-subject prediction accuracy.
- Trained the model using EMG signals, joint angles, and muscle forces to predict knee joint torque.
Main Results:
- The hybrid-CNN model achieved significantly low error (RMSE ≤0.16 Nm/kg) for within-subject knee joint torque prediction.
- Transfer learning significantly improved inter-subject prediction generalizability, reducing error (RMSE ≤0.14 Nm/kg).
Conclusions:
- The developed transfer learning-enhanced CNN-GRU-Attention model shows significant potential for accurate knee joint torque prediction.
- This approach offers a promising tool for enhancing sports performance and injury prevention strategies.
- The study highlights the effectiveness of hybrid models and transfer learning in complex biomechanical analyses.

