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Related Concept Videos

Preparation of Samples for Electron Microscopy01:20

Preparation of Samples for Electron Microscopy

To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...
Ion-Exchange Chromatography01:09

Ion-Exchange Chromatography

Ion-exchange chromatography, or IEC, is a technique for separating ions based on their affinity for the stationary phase. The stationary phase is a cross-linked polymer resin with covalently attached ionic functional groups. The functional groups can be either positively charged (cation exchangers) or negatively charged (anion exchangers). A cation exchanger consists of a polymeric anion and active cations, while an anion exchanger is a polymeric cation with active anions. The choice of...

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An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
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Functional Hydrogels for Implantable Bioelectronic Devices.

Mingxi Tu1,2, Tianming Zhao1, Hongji Guo1

  • 1State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China.

Luminescence : the Journal of Biological and Chemical Luminescence
|March 18, 2025
PubMed
Summary
This summary is machine-generated.

Functionalized hydrogels offer promising solutions for implantable bioelectronic devices due to their conductivity, self-healing, and adhesion properties. This review highlights their design and application in advanced medical diagnostics and treatments.

Keywords:
biocompatibilitybiosensinghydrogelimplantable bioelectronic devices

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Bioelectronics

Background:

  • Implantable electronic devices require materials with conductivity, flexibility, and biocompatibility for stable operation in vivo.
  • Hydrogels, with their tissue-like properties and tunable functionalities, are emerging as key materials for advanced biomedical applications.

Purpose of the Study:

  • To review research progress in molecular design and performance modulation of functionalized hydrogels.
  • To summarize the application of functionalized hydrogels in implantable bioelectronic devices.
  • To discuss future challenges and opportunities in this field.

Main Methods:

  • Review of literature on functionalized hydrogels focusing on conductivity, self-healing, adhesion, and toughness.
  • Analysis of molecular design strategies for property modulation.
  • Summarization of recent advancements in implantable bioelectronic device applications.

Main Results:

  • Functionalized hydrogels exhibit tunable conductivity, self-healing, adhesion, and toughness, crucial for implantable devices.
  • Recent progress demonstrates their potential in various implantable bioelectronic applications.
  • Key design principles and modulation strategies are identified.

Conclusions:

  • Hydrogel-based implantable bioelectronic devices represent a significant future direction in the biomedical field.
  • Continued research in molecular design and property modulation will enhance their performance and applicability.
  • Addressing current challenges will unlock the full potential of hydrogels for in vivo applications.